Sleep spindles: validated concepts and breakthroughs

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Sleep Spindles: Validated Concepts and Breakthroughs

Introduction: Sleep spindles, the hallmark of sleep synchronization in stage 2 non-REM sleep, are rhythmic and monomorphic waves, between 10 and 14 Hz, with a maximum amplitude in the vertex (Cz), with bilateral irradiation to central regions (C3 and C4). Objective: In this article we present an overview of sleep spindles ranging from well established concepts of morphology, generation mechanis...

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The development of EEC sleep-spindles in prematurely-born and full-term infants was studied to test an hypothesized impact of experience (longer extrauterine existence) upon innate maturational factors (EEG development). The age of otiset of sleep spindles and achievement of mature spindle quality occurs approximately 4 weeks earlier in prematurely-born infants than in full-term infants. Sleep ...

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Characterization of Sleep Spindles

Local Field Potential (LFP) measurements from sleep data is important in Neurological studies because experiments have shown a correlation between sleep and memory consolidation [1]. The most prominent of the coherent signals within LFP sleep data are spindles, which occur most often when a person is dozing off, durring Stage 2 of Non-Rapid-Eye-Movement (NREM) sleep [2]. Determining the specifi...

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ARMA Modelling of Sleep Spindles

Differences in EEG sleep spindles constitute a promising indicator of neurodegenerative disorders. In this paper an ARMA modelling to sleep spindles is proposed and tested. The primary objective is to distinguish, via poles and zeros location, between regular, elderly and dementia subjects. In order to achieve this goal, a model validation has been done.

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Sleep spindles and hippocampal functional connectivity in human NREM sleep.

We investigated human hippocampal functional connectivity in wakefulness and throughout non-rapid eye movement sleep. Young healthy subjects underwent simultaneous EEG and functional magnetic resonance imaging (fMRI) measurements at 1.5 T under resting conditions in the descent to deep sleep. Continuous 5 min epochs representing a unique sleep stage (i.e., wakefulness, sleep stages 1 and 2, or ...

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ژورنال

عنوان ژورنال: Journal of Epilepsy and Clinical Neurophysiology

سال: 2007

ISSN: 1676-2649

DOI: 10.1590/s1676-26492007000400006